Bioprinting

Leader of research group: Prof. Dr. Judit Pongrácz

MS

The group's activities

Bioprinting, or tissue printing, is a central part of a process that is preceded by cell culture using conventional methods or in a bioreactor, followed by the maturation of the finished tissue. The activities broken down to persons below can all be grouped around the diverse application, service, research, and potential clinical use of this process. These include: modeling of common (e.g. cancerous) and rare (e.g. genetic) diseases, magnetic aggregation of cell cultures that are difficult to aggregate, traditional (cell culture) and alternative (e.g. toxicological, stem cell differentiation) use of the bioreactor system, nanotechnological materials science innovation, artificial neural network data analysis, professional language activities to ensure the display of data in publications and education, etc.

Commitments

Topics of current and planned educational activities

  • In the UPMS Biotechnology Master’s program: Advanced Tissue Cultures (compulsory subject)
  • In the UP MIK Bioengineer Master’s program: 3D Bioprinting (elecitve subject)

Topics of current and planned patents

  • Research and clinical applications of 3D lung reaggregation cultures
  • Applications of nanotechnological steroid products
  • Creating personalized bone and cartilage tissue through 3D culture
  • Use of toxicological homonculus to test new active substances

Researchers

Dr. Elhusseiny MM Abdelwahab

assistant professor

Krisztina Bánfai

assistant professor

Judit Bóvári-Biri

postdoctoral fellow

Dr. Veronika Csöngei

senior lecturer

Dr. Luca Járomi

senior lecturer

Dr. Krisztián Kvell

associate professor

Levente Ornódi

lab technician

Dr. Szilárd Pál

senior lecturer

Prof. Dr. Judit Pongrácz

full professor, head of unit

Dr. Aleksandar Széchenyi

research professor (junior)

Projects

3D Bioprinting with special regard to lung diseases and modeling of their vascular network

  • Prof. Dr. Judit Pongrácz
  • Dr. Veronika Csöngei
  • Dr. Luca Járomi
  • Dr. Aldelwahab Mohamed Elhusseiny

Leading the bioprinting working group, with special regard to lung and vascular diseases and applications, preparation of clinical use through OGYÉI negotiations (Prof. Dr. Judit Pongrácz)

Creation of a 3D blood-brain barrier model, especially with the aim of studying the penetration of lung tumors (Dr. Veronika Csöngei)

3D aggregation of aggregation-resistant lung tissues through the application of magnetic methods (Dr. Luca Járomi)

Modeling of LAM (lymphangioleiomyomatosis), a rare human lung disease of genetic origin with human cell lines and primary cultures (Dr. Aldelwahab Mohamed Elhusseiny)

Traditional and alternative areas of application of the 3D bioreactor

  • Dr. Krisztián Kvell
  • Krisztina Bánfai
  • Judit Bóvári-Biri
  • Levente Ornódi

Leading the bioreactor working group in both traditional (culture) and alternative (toxicology, stem cell differentiation) areas of application (Dr. Krisztián Kvell)

Development of toxicological homunculus (human organ systems) in a 3D bioreactor, validation with known active substances and preparation for testing new active ingredients (Krisztina Bánfai)

Study of the tissue differentiation of stem cells (primary or induced) in a 3D bioreactor concerning bone and cartilage tissue (Judit Bóvári-Biri)

Preparation of the 3D bioreactor for regular and temporary, cellular and other activities (Levente Ornódi)

Further scientific activities

  • Dr. Szilárd Pál
  • Dr. Alexander Széchenyi
  • Dr. György Miskei

Artificial neural network data evaluation (Dr. Szilárd Pál)

Nanotechnological materials science innovations (Dr. Alexander Széchenyi)

Professional English language activity in the development of publications and teaching materials (Dr. György Miskei)

Gallery